Last update: October 1st, 2019
Treatment and management of primary immunodeficiencies involves different points:
- Preventing and treating infections appearing due to the immune dysfunction which mainly implies the use of antibiotics.
- Boosting the immune system with growth factors, interferon therapy or the most commonly immunoglobulin therapy. Depending on the specific deficiencies, the deficiency of the immune system can be supplied by adding an external treatment.
- Correcting the underlying causes of the immunodeficiency which can be achieved for example with stem cell transplantations.
- Specific treatment related to other disorders (cancer or autoimmune diseases) that cause also immune alterations.
- McCusker C, Warrington R. Primary immunodeficiency. Allergy Asthma Clin Immunol. 2011 Nov;7 Suppl 1(Suppl 1):S11. Go to publication
- Mahlaoui N, et al. Advances in the Care of Primary Immunodeficiencies (PIDs): from Birth to Adulthood. J Clin Immunol. 2017;37(5):452-60. Go to publication
- McCusker C, Upton J, Warrington R. Primary immunodeficiency. Allergy Asthma Clin Immunol. 2018 Sep;14(Suppl 2):61. Go to publication
- Modell V, et al. Global overview of primary immunodeficiencies: a report from Jeffrey Modell Centers worldwide focused on diagnosis, treatment, and discovery. Immunol Res.2014 Sep;60(1):132-44. Go to publication