Lymphoclonal™-12 is an 8-color mixture including 12 antibodies, designed to simultaneously determine, in peripheral blood, bone marrow and other body fluids, the major lymphocyte subpopulations including T-cells (CD3+), B-cells (CD19+ CD20+) and NK-cells (CD3- CD56+), as well as helper (CD3+ CD4+) and cytotoxic (CD3+ CD8+) T-cell subsets and B-cell subsets with light chain immunophenotype Kappa (CD19+ SmIgκ+) and Lambda (CD19+ SmIgλ+).
In comparison to the Lymphoclonal™-9 kit, this combination also includes CD5 and CD10 antibodies, making possible complete assessment of normal B-cell maturation and subclassification of B-cell lymphoma, and CD38 antibody for the identification of other leukocyte populations (e.g. plasma cells). Likewise, the lyophilized form provides a more stable mixture.
|CD4 + CD20
||CD8 + SmIgLambda
||CD56 + SmIgKappa
||CD3 + CD10
B-cell stages analysis in a bone marrow sample stained with Lymphoclonal™-12
*Nguyen V et al. Customised single tube 14 parameter, 8 colour Lymphoma Screening Panel. Poster session at: 38th Annual Scientific Meeting Australasian Cytometry Society; 2015 Oct 11-14; Perth, Australia.
Pacific Blue™ is a trademark of Life Technologies Corporation
For the RESEARCH FIELD:
This product is provided under an intellectual property license from Life Technologies Corporation. The Purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components for any Commercial Purposes. Commercial Purposes means any activity by a party to generate revenue, which may include, but is not limited to use of the product or its components: (1) in manufacturing or in quality assurance or quality control of a commercial product; (2) to provide a service, information, or data for a free or other consideration; (3) for therapeutic or prophylactic purposes; (4) for diagnostic use; and (5) for resale, whether or not such items are resold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].
For the DIAGNOSTICS FIELD:
This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product for use in the identification, staging, determination of predisposition, diagnosis, prognosis, monitoring or trea™ent of human disease. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or [email protected].