MM MRD Kit is comprised of a pre-mixed 6-color 8-antibody combination and two single antibody vials: CD138-BV421 and CD27-BV510. This kit is designed for the accurate identification and discrimination of malignant and normal plasma cells (PCs) research in bone marrow samples.

The MM MRD kit is carefully designed to specifically recognize by flow cytometry the following antigens CD138, CD27, CD38, CD56, CD45, CD19, CD117, CD81, cytoplasmic IgKappa and IgLambda. The light chains used for clonality assessment are polyclonal. The use of polyclonal instead over monoclonal antibodies has demonstrated advantages for the detection of intracellular immunoglobulin light chains in the clonality assessment of PCs.

The kit is composed of

  • Lyophilized Antibody Combination Tube 1:
    • Four (4) lyophilized vials of 5 tests for surface staining that contain:
      • Anti-human CD38-FITC antibody, multi-epitope.
      • Anti-human CD56-PE antibody, clone: C5.9, isotype: IgG2b.
      • Anti-human CD45-PerCP-Cyanine 5.5 antibody, clone: EO1, isotype: IgG2b.
      • Anti-human CD19-PE-Cyanine7 antibody, clone: SA287, isotype: IgG1.
      • Anti-human CD117-APC antibody, clone: 104D2, isotype: IgG1.
      • Anti-human CD81-APC-C750™ antibody, clone: M38, isotype: IgG1.
  • Lyophilized Antibody Combination Tube 2:
    • Four (4) lyophilized vials of 5 tests each for surface staining that contain:
      • Anti-human CD38-FITC antibody, multi-epitope.
      • Anti-human CD56-PE antibody, clone: C5.9, isotype: IgG2b.
      • Anti-human CD45-PerCP-Cyanine 5.5 antibody, clone: EO1, isotype: IgG2b.
      • Anti-human CD19-PE-Cyanine7 antibody, clone: SA287, isotype: IgG1.
    • Four (4) lyophilized vials of 5 tests each for cytoplasmic staining that contain:
      • Anti-human CyIgκ-APC goat antibody, clone: polyclonal.
      • Anti-human CyIgλ-APC-C750™ goat antibody, clone: polyclonal.
  • Antibody vials in liquid format:
    • Two (2) liquid antibody vials of:
      • Anti-human CD138-BV421 antibody, clone: MI15, isotype: IgG1
      • Anti-human CD27-BV510 antibody, clone: O323, isotype: IgG1