CD38multi-epitope is a polyclonal antibody that recognizes multiple epitopes on CD38, enabling its detection on plasma cells, even in patients undergoing anti-CD38 therapy.

BD Cytognos has developed an innovative CD38 multi‑epitope antibody specifically designed to overcome therapeutic antibody interference. BD Cytognos™ CD38 multi‑epitope FITC ensures robust and reliable detection of CD38‑positive cells even in patients treated with anti‑CD38 therapies such as daratumumab.

Comparative evaluation by flow cytometry of CD38-FITC multi-epitope performance.
Dot plots from unstained cells (left panel), stained cells treated with Daratumumab Buffer (middle panel), or stained cells treated with Daratumumab (right panel).