The mechanism of phagocytosis is part of the innate immune response, essential for the protection of the organism. The failure of this activity results in recurrent and chronic bacterial and fungal infections.
Phagocytic activity should be studied to confirm or exclude defects that result in primary and secondary immunodeficiencies. Flow cytometry techniques in the study of the phagocytic activity of neutrophils and monocytes has certain advantages over other methods: permit the evaluation of relatively small samples (important in young children and infants) and it is a quick method to study simultaneously biochemical and functional characteristics.
Cytognos offers an antibody product line optimal for phagocytic activity.